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High Glucose-induced Retinal Pericyte Apoptosis Depends on Association of GAPDH and Siah1

Diabetic retinopathy (DR) is a leading cause of blindness worldwide, and its prevalence is growing. Current therapies for DR address only the later stages of the disease, are invasive, and have limited effectiveness. Retinal pericyte death is an early pathologic feature of DR. Although it has been o...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Suarez, Sandra, McCollum, Gary W., Jayagopal, Ashwath, Penn, John S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653686/
https://ncbi.nlm.nih.gov/pubmed/26438826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.682385
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