In Vivo Imaging of Retinal Hypoxia Using HYPOX-4-Dependent Fluorescence in a Mouse Model of Laser-Induced Retinal Vein Occlusion (RVO)

PURPOSE: To demonstrate the utility of a novel in vivo molecular imaging probe, HYPOX-4, to detect and image retinal hypoxia in real time, in a mouse model of retinal vein occlusion (RVO). METHODS: Retinal vein occlusion was achieved in adult mice by photodynamic retinal vein thrombosis (PRVT). One...

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Dades bibliogràfiques
Publicat a:Invest Ophthalmol Vis Sci
Autors principals: Uddin, Md. Imam, Jayagopal, Ashwath, McCollum, Gary W., Yang, Rong, Penn, John S.
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2017
Matèries:
Retina
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531786/
https://ncbi.nlm.nih.gov/pubmed/28750413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-21187
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