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Endoglin Promotes Angiogenesis in Cell- and Animal-Based Models of Retinal Neovascularization

PURPOSE. We investigated endoglin expression in hypoxic microvascular endothelial cells and retinal endoglin expression in rats that develop experimental oxygen-induced retinopathy (OIR). We also tested neutralizing antibodies (Abs) against endoglin (anti-CD105 Ab) and VEGF (anti-VEGF Ab) either alo...

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Detalhes bibliográficos
Main Authors: Barnett, Joshua M., Suarez, Sandra, McCollum, Gary W., Penn, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197712/
https://ncbi.nlm.nih.gov/pubmed/25159209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14945
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