Saturation Mutagenesis of the Antithrombin Reactive Center Loop P14 Residue Supports a Three-step Mechanism of Heparin Allosteric Activation Involving Intermediate and Fully Activated States

Ítems similars

• How Antithrombin Activates Heparin♦: Saturation Mutagenesis of the Antithrombin Reactive Center Loop P14 Residue Supports a Three-step Mechanism of Heparin Allosteric Activation Involving Intermediate and Fully Activated States
  Publicat: (2015)
• The Allosteric Mechanism of Activation of Antithrombin as an Inhibitor of Factor IXa and Factor Xa: HEPARIN-INDEPENDENT FULL ACTIVATION THROUGH MUTATIONS ADJACENT TO HELIX D
  per: Dementiev, Alexey, et al.
  Publicat: (2013)
• COOPERATIVE INTERACTIONS OF THREE HOTSPOT HEPARIN BINDING RESIDUES ARE CRITICAL FOR ALLOSTERIC ACTIVATION OF ANTITHROMBIN BY HEPARIN
  per: Richard, Benjamin, et al.
  Publicat: (2018)
• Conformational Activation of Antithrombin by Heparin Involves an Altered Exosite Interaction with Protease
  per: Izaguirre, Gonzalo, et al.
  Publicat: (2014)
• The heparin-binding site of antithrombin is crucial for antiangiogenic activity
  per: Zhang, Weiqing, et al.
  Publicat: (2005)