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The heparin-binding site of antithrombin is crucial for antiangiogenic activity

The heparin-binding site of antithrombin is shown here to play a crucial role in mediating the antiangiogenic activity of conformationally altered cleaved and latent forms of the serpin. Blocking the heparin-binding site of cleaved or latent antithrombin by complexation with a high-affinity heparin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhang, Weiqing, Swanson, Richard, Izaguirre, Gonzalo, Xiong, Yan, Lau, Lester F., Olson, Steven T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society of Hematology 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895214/
https://ncbi.nlm.nih.gov/pubmed/15905187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-02-0547
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