Impact of normalization methods on high-throughput screening data with high hit rates and drug testing with dose–response data

Motivation: Most data analysis tools for high-throughput screening (HTS) seek to uncover interesting hits for further analysis. They typically assume a low hit rate per plate. Hit rates can be dramatically higher in secondary screening, RNAi screening and in drug sensitivity testing using biological...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Bioinformatics
Autori principali: Mpindi, John-Patrick, Swapnil, Potdar, Dmitrii, Bychkov, Jani, Saarela, Saeed, Khalid, Wennerberg, Krister, Aittokallio, Tero, Östling, Päivi, Kallioniemi, Olli
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Original Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653387/
https://ncbi.nlm.nih.gov/pubmed/26254433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv455
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi