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Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states

Chromatin condensation plays an important role in the regulation of gene expression. Recently, it was shown that the transcriptional activation of Hoxd genes during vertebrate digit development involves modifications in 3D interactions within and around the HoxD gene cluster. This reorganization fol...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fabre, Pierre J., Benke, Alexander, Joye, Elisabeth, Nguyen Huynh, Thi Hanh, Manley, Suliana, Duboule, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653165/
https://ncbi.nlm.nih.gov/pubmed/26504220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517972112
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