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Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states

Chromatin condensation plays an important role in the regulation of gene expression. Recently, it was shown that the transcriptional activation of Hoxd genes during vertebrate digit development involves modifications in 3D interactions within and around the HoxD gene cluster. This reorganization fol...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Fabre, Pierre J., Benke, Alexander, Joye, Elisabeth, Nguyen Huynh, Thi Hanh, Manley, Suliana, Duboule, Denis
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653165/
https://ncbi.nlm.nih.gov/pubmed/26504220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517972112
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