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HoxD cluster scanning deletions identify multiple defects leading to paralysis in the mouse mutant Ironside

A spontaneous semidominant mutation (Ironside, Irn) was isolated in mice, leading to severe hindlimb paralysis following multiple deletions in cis at the HoxD locus. To understand its cellular and molecular etiology, we embarked on a comparative analysis using systematic HoxD cluster deletions, prod...

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Detalhes bibliográficos
Main Authors: Tarchini, Basile, Huynh, Thi Hanh Nguyen, Cox, Greg A., Duboule, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315393/
https://ncbi.nlm.nih.gov/pubmed/16322559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.351105
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