Genomic characterization of a large panel of patient-derived hepatocellular carcinoma xenograft tumor models for preclinical development

Lack of clinically relevant tumor models dramatically hampers development of effective therapies for hepatocellular carcinoma (HCC). Establishment of patient-derived xenograft (PDX) models that faithfully recapitulate the genetic and phenotypic features of HCC becomes important. In this study, we fi...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Gu, Qingyang, Zhang, Bin, Sun, Hongye, Xu, Qiang, Tan, Yexiong, Wang, Guan, Luo, Qin, Xu, Weiguo, Yang, Shuqun, Li, Jian, Fu, Jing, Chen, Lei, Yuan, Shengxian, Liang, Guibai, Ji, Qunsheng, Chen, Shu-Hui, Chan, Chi-Chung, Zhou, Weiping, Xu, Xiaowei, Wang, Hongyang, Fang, Douglas D.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652995/
https://ncbi.nlm.nih.gov/pubmed/26062443
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