Growth Suppression of Human Hepatocellular Carcinoma Xenografts by a Monoclonal Antibody CH12 Directed to Epidermal Growth Factor Receptor Variant III

Human hepatocellular carcinoma (HCC) is considered difficult to cure because it is resistant to radio- and chemotherapy and has a high recurrence rate after curative liver resection. Epidermal growth factor receptor variant III (EGFRvIII) has been reported to express in HCC tissues and cell lines. T...

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Main Authors: Jiang, Hua, Wang, Huamao, Tan, Zhonghua, Hu, Suwen, Wang, Hai, Shi, Bizhi, Yang, Lin, Li, Peiyong, Gu, Jianren, Wang, Hongyang, Li, Zonghai
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037704/
https://ncbi.nlm.nih.gov/pubmed/21163950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.192252
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