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Identification of an Exon 4-Deletion Variant of Epidermal Growth Factor Receptor with Increased Metastasis-Promoting Capacity
Several types of epidermal growth factor receptor (EGFR) gene alternations have been observed in human tumors. Here we present a novel EGFR variant with aberrant splicing of exon 4 (named as de4 EGFR). Variant-specific polymerase chain reaction showed that de4 EGFR was expressed in some glioma (4/40...
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Main Authors: | , , , , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
Elsevier
2011-05-01
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叢編: | Neoplasia: An International Journal for Oncology Research |
在線閱讀: | http://www.sciencedirect.com/science/article/pii/S1476558611800643 |
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