Fine-Tuned Expression of Programmed Death 1 Ligands in Mature Dendritic Cells Stimulated by CD40 Ligand Is Critical for the Induction of an Efficient Tumor Specific Immune Response

During maturation, murine myeloid dendritic cells (DCs) upregulated the expressions of CD11c, CD25, CD40, CD80, CD86, MHC II and programmed death 1 ligands 1 and 2 (PD-L1 and PD-L2). Differential expression patterns of PD-L1 and PD-L2 were found when DCs were triggered by CD40 ligand and TNF-α. PD-L...

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Publicat a:Cell Mol Immunol
Autors principals: Gu, Tao, Zhu, Yibei, Chen, Cheng, Li, Min, Chen, Yongjing, Yu, Gehua, Ge, Yan, Zhou, Shiyong, Zhou, Huan, Huang, Yong, Qiu, Yuhua, Zhang, Xueguang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652915/
https://ncbi.nlm.nih.gov/pubmed/18318992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2008.4
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