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Removing unwanted variation in a differential methylation analysis of Illumina HumanMethylation450 array data

Due to their relatively low-cost per sample and broad, gene-centric coverage of CpGs across the human genome, Illumina's 450k arrays are widely used in large scale differential methylation studies. However, by their very nature, large studies are particularly susceptible to the effects of unwan...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Maksimovic, Jovana, Gagnon-Bartsch, Johann A., Speed, Terence P., Oshlack, Alicia
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652745/
https://ncbi.nlm.nih.gov/pubmed/25990733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv526
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