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Using control genes to correct for unwanted variation in microarray data

Microarray expression studies suffer from the problem of batch effects and other unwanted variation. Many methods have been proposed to adjust microarray data to mitigate the problems of unwanted variation. Several of these methods rely on factor analysis to infer the unwanted variation from the dat...

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Autores principales: Gagnon-Bartsch, Johann A., Speed, Terence P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577104/
https://ncbi.nlm.nih.gov/pubmed/22101192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxr034
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