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Using control genes to correct for unwanted variation in microarray data

Microarray expression studies suffer from the problem of batch effects and other unwanted variation. Many methods have been proposed to adjust microarray data to mitigate the problems of unwanted variation. Several of these methods rely on factor analysis to infer the unwanted variation from the dat...

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Autori principali: Gagnon-Bartsch, Johann A., Speed, Terence P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577104/
https://ncbi.nlm.nih.gov/pubmed/22101192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxr034
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