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High-throughput sequencing insights into T-cell receptor repertoire diversity in aging
Decline in T-cell generation leading to T-cell receptor repertoire contraction is a cornerstone of immune system aging, and consequent disorders. High-throughput sequencing enables in-depth immune repertoire characterization, but blood samples are too small to capture its total diversity. New comput...
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| Veröffentlicht in: | Genome Med |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4652363/ https://ncbi.nlm.nih.gov/pubmed/26582264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0242-3 |
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