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Aging and T-cell diversity

Naïve and memory CD4 and CD8 T cells represent a highly dynamic system with constant homeostatic and antigen-driven proliferation, influx, and loss of T cells. Thymic activity dwindles with age and essentially ceases in the later decades of life, severely constraining the generation of new T cells....

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Detalhes bibliográficos
Main Authors: Goronzy, Jörg J., Lee, Won-Woo, Weyand, Cornelia M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680153/
https://ncbi.nlm.nih.gov/pubmed/17218073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2006.11.016
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