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Successful and Maladaptive T Cell Aging

Throughout life, the T cell system adapts to shifting resources and demands, resulting in a fundamentally restructured immune system in older individuals. Here we review the cellular and molecular features of an aged immune system and discuss the trade-offs inherent to these adaptive mechanisms. Pro...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Goronzy, Jörg J., Weyand, Cornelia M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433436/
https://ncbi.nlm.nih.gov/pubmed/28329703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.03.010
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