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In vivo evidence against the existence of antiprogestins disrupting receptor binding to DNA.

The binding of a steroid hormone to its receptor elicits a sequence of events: activation of the receptor (probably through dissociation from a complex of heat shock proteins), dimerization, binding to hormone responsive elements, and finally modulation of gene transcription. RU 486, the first antip...

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Detalhes bibliográficos
Main Authors: Delabre, K, Guiochon-Mantel, A, Milgrom, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC46523/
https://ncbi.nlm.nih.gov/pubmed/8506282
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