Antiprogestins prevent progesterone receptor binding to hormone responsive elements in vivo.
Antiprogestins inhibit progesterone action by competing for binding to the progesterone receptor and are potentially important pharmaceuticals in fertility control and cancer therapy. Why the complex of antiprogestins and progesterone receptor is functionally inactive is unclear. Present models are...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45225/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7972059/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.24.11333 |
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