In vivo functional protein-protein interaction: nuclear targeted hsp90 shifts cytoplasmic steroid receptor mutants into the nucleus.

In target tissue extracts, heat shock protein hsp90 has been found associated to all unliganded steroid receptors. Modulation of important functions of these receptors, including prevention of DNA binding and optimization of transcriptional activity, has been attributed to hsp90. However no unequivo...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kang, K I, Devin, J, Cadepond, F, Jibard, N, Guiochon-Mantel, A, Baulieu, E E, Catelli, M G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42943/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8278390/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.1.340
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