In vivo functional protein-protein interaction: nuclear targeted hsp90 shifts cytoplasmic steroid receptor mutants into the nucleus.

In target tissue extracts, heat shock protein hsp90 has been found associated to all unliganded steroid receptors. Modulation of important functions of these receptors, including prevention of DNA binding and optimization of transcriptional activity, has been attributed to hsp90. However no unequivo...

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Autores principales: Kang, K I, Devin, J, Cadepond, F, Jibard, N, Guiochon-Mantel, A, Baulieu, E E, Catelli, M G
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC42943/
https://ncbi.nlm.nih.gov/pubmed/8278390
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