Direct Reprogramming of Human Primordial Germ Cells into Induced Pluripotent Stem Cells: Efficient Generation of Genetically Engineered Germ Cells

Primordial germ cells (PGCs) share many properties with embryonic stem cells (ESCs) and innately express several key pluripotency-controlling factors, including OCT4, NANOG, and LIN28. Therefore, PGCs may provide a simple and efficient model for studying somatic cell reprogramming to induced pluripo...

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Bibliographische Detailangaben
Veröffentlicht in:Stem Cells Dev
Hauptverfasser: Bazley, Faith A., Liu, Cyndi F., Yuan, Xuan, Hao, Haiping, All, Angelo H., De Los Angeles, Alejandro, Zambidis, Elias T., Gearhart, John D., Kerr, Candace L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2015
Schlagworte:
Original Research Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652187/
https://ncbi.nlm.nih.gov/pubmed/26154167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0100
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