Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection

Dendritic cells can capture and transfer retroviruses in vitro across synaptic cell-cell contacts to uninfected cells, a process called trans-infection. Whether trans-infection contributes to retroviral spread in vivo remains unknown. Here, we visualize how retroviruses disseminate in secondary lymp...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Sewald, Xaver, Ladinsky, Mark S., Uchil, Pradeep D., Beloor, Jagadish, Pi, Ruoxi, Herrmann, Christin, Motamedi, Nasim, Murooka, Thomas T., Brehm, Michael A., Greiner, Dale L., Shultz, Leonard D., Mempel, Thorsten R., Bjorkman, Pamela J., Kumar, Priti, Mothes, Walther
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651917/
https://ncbi.nlm.nih.gov/pubmed/26429886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab2749
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