Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection

Dendritic cells can capture and transfer retroviruses in vitro across synaptic cell-cell contacts to uninfected cells, a process called trans-infection. Whether trans-infection contributes to retroviral spread in vivo remains unknown. Here, we visualize how retroviruses disseminate in secondary lymp...

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Veröffentlicht in:Science
Hauptverfasser: Sewald, Xaver, Ladinsky, Mark S., Uchil, Pradeep D., Beloor, Jagadish, Pi, Ruoxi, Herrmann, Christin, Motamedi, Nasim, Murooka, Thomas T., Brehm, Michael A., Greiner, Dale L., Shultz, Leonard D., Mempel, Thorsten R., Bjorkman, Pamela J., Kumar, Priti, Mothes, Walther
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651917/
https://ncbi.nlm.nih.gov/pubmed/26429886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab2749
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