IL-17 functions through the novel REG3β-JAK2-STAT3 inflammatory pathway to promote the transition from chronic pancreatitis to pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) offers an optimal model for discovering “druggable” molecular pathways that participate in inflammation-associated cancer development. Chronic pancreatitis, a common prolonged inflammatory disease, behaves as a well-known premalignant condition that contribute...

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Dettagli Bibliografici
Pubblicato in:Cancer Res
Autori principali: Loncle, Celine, Bonjoch, Laia, Folch-Puy, Emma, Lopez-Millan, Maria Belen, Lac, Sophie, Molejon, Maria Inés, Chuluyan, Eduardo, Cordelier, Pierre, Dubus, Pierre, Lomberk, Gwen, Urrutia, Raul, Closa, Daniel, Iovanna, Juan L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651828/
https://ncbi.nlm.nih.gov/pubmed/26404002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0896
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