Systemic Vascular Transduction by Capsid Mutant Adeno-Associated Virus After Intravenous Injection

The ability to effectively deliver genetic material to vascular endothelial cells remains one of the greatest unmet challenges facing the development of gene therapies to prevent diseases with underlying vascular etiology, such as diabetes, atherosclerosis, and age-related macular degeneration. Here...

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Bibliographische Detailangaben
Veröffentlicht in:Hum Gene Ther
Hauptverfasser: Lipinski, Daniel M., Reid, Chris A., Boye, Sanford L., Peterson, James J., Qi, Xiaoping, Boye, Shannon E., Boulton, Michael E., Hauswirth, William W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2015
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651034/
https://ncbi.nlm.nih.gov/pubmed/26359319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2015.097
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