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Vaccinia virus as a subhelper for AAV replication and packaging

Adeno-associated virus (AAV) has been widely used as a gene therapy vector to treat a variety of disorders. While these vectors are increasingly popular and successful in the clinic, there is still much to learn about the viruses. Understanding the biology of these viruses is essential in engineerin...

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Dettagli Bibliografici
Pubblicato in:Mol Ther Methods Clin Dev
Autori principali: Moore, Andrea R, Dong, Biao, Chen, Lingxia, Xiao, Weidong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650997/
https://ncbi.nlm.nih.gov/pubmed/26636113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2015.44
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