Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties

The conserved histone methyltransferase Dot1 establishes an H3K79 methylation pattern consisting of mono-, di- and trimethylation states on histone H3 via a distributive mechanism. This mechanism has been shown to be important for the regulation of the different H3K79 methylation states in yeast. Do...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Stulemeijer, Iris J. E., De Vos, Dirk, van Harten, Kirsten, Joshi, Onkar K., Blomberg, Olga, van Welsem, Tibor, Terweij, Marit, Vlaming, Hanneke, de Graaf, Erik L., Altelaar, A. F. Maarten, Bakker, Barbara M., van Leeuwen, Fred
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650758/
https://ncbi.nlm.nih.gov/pubmed/25965993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09824
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