Targeting Mdmx to treat breast cancers with wild-type p53

The function of the tumor suppressor p53 is universally compromised in cancers. It is the most frequently mutated gene in human cancers (reviewed). In cases where p53 is not mutated, alternative regulatory pathways inactivate its tumor suppressive functions. This is primarily achieved through elevat...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Cell Death Dis
Huvudupphovsmän: Haupt, S, Buckley, D, Pang, J-MB, Panimaya, J, Paul, P J, Gamell, C, Takano, E A, Ying Lee, Y, Hiddingh, S, Rogers, T-M, Teunisse, A F A S, Herold, M J, Marine, J-C, Fox, S B, Jochemsen, A, Haupt, Y
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2015
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650725/
https://ncbi.nlm.nih.gov/pubmed/26181202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.173
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk