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Tight junction CLDN2 gene is a direct target of the vitamin D receptor

The breakdown of the intestinal barrier is a common manifestation of many diseases. Recent evidence suggests that vitamin D and its receptor VDR may regulate intestinal barrier function. Claudin-2 is a tight junction protein that mediates paracellular water transport in intestinal epithelia, renderi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Yong-guo, Wu, Shaoping, Lu, Rong, Zhou, David, Zhou, Jingsong, Carmeliet, Geert, Petrof, Elaine, Claud, Erika C., Sun, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650691/
https://ncbi.nlm.nih.gov/pubmed/26212084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10642
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