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Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma

P300/CBP-associated factor (PCAF), a histone acetyltransferase (HAT), has been found to regulate numerous cell signaling pathways controlling cell fate by acetylating both histone and non-histone proteins. We previously reported that PCAF upregulates cell apoptosis by inactivating Serine/Threonine P...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Gai, X, Tu, K, Li, C, Lu, Z, Roberts, L R, Zheng, X
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650545/
https://ncbi.nlm.nih.gov/pubmed/25855960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.76
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