Myelin-associated glycoprotein modulates apoptosis of motoneurons during early postnatal development via NgR/p75(NTR) receptor-mediated activation of RhoA signaling pathways

Myelin-associated glycoprotein (MAG) is a minor constituent of nervous system myelin, selectively expressed on the periaxonal myelin wrap. By engaging multiple axonal receptors, including Nogo-receptors (NgRs), MAG exerts a nurturing and protective effect the axons it ensheaths. Pharmacological acti...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Palandri, A, Salvador, V R, Wojnacki, J, Vivinetto, A L, Schnaar, R L, Lopez, P H H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650434/
https://ncbi.nlm.nih.gov/pubmed/26335717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.228
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