Molecular Basis of the Interactions of the Nogo-66 Receptor and Its Homolog NgR2 with Myelin-Associated Glycoprotein: Development of NgR(OMNI)-Fc, a Novel Antagonist of CNS Myelin Inhibition

Myelin-associated glycoprotein (MAG) is a sialic acid-binding Ig-family lectin that functions in neuronal growth inhibition and stabilization of axon–glia interactions. The ectodomain of MAG is comprised of five Ig-like domains and uses neuronal cell-type-specific mechanisms to signal growth inhibit...

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Hlavní autoři: Robak, Laurie A., Venkatesh, Karthik, Lee, Hakjoo, Raiker, Stephen J., Duan, Yuntao, Lee-Osbourne, Jane, Hofer, Thomas, Mage, Rose G., Rader, Christoph, Giger, Roman J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779053/
https://ncbi.nlm.nih.gov/pubmed/19420245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4935-08.2009
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