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Controversies concerning thymus-derived regulatory T cells: fundamental issues and a new perspective

Thymus-derived regulatory T cells (Tregs) are considered to be a distinct T-cell lineage that is genetically programmed and specialised for immunosuppression. This perspective is based on the key evidence that CD25(+) Tregs emigrate to neonatal spleen a few days later than other T cells and that thy...

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Detalhes bibliográficos
Publicado no:Immunol Cell Biol
Main Authors: Ono, Masahiro, Tanaka, Reiko J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650266/
https://ncbi.nlm.nih.gov/pubmed/26215792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2015.65
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