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Cutting Edge: Hematopoietic-Derived APCs Select Regulatory T Cells in Thymus

Recognition of self-peptide–MHC complexes by high-affinity TCRs and CD28 signaling are critical for the development of forkhead-winged helix box transcription factor 3(+) regulatory T cells (Tregs) in thymus. However, the type of APCs that are responsible for selecting Tregs has remained unclear. To...

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Autors principals: Román, Eulogia, Shino, Hanabuchi, Qin, F. Xiao-Feng, Liu, Yong Jun
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325783/
https://ncbi.nlm.nih.gov/pubmed/20802149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900665
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