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Cutting Edge: Hematopoietic-Derived APCs Select Regulatory T Cells in Thymus
Recognition of self-peptide–MHC complexes by high-affinity TCRs and CD28 signaling are critical for the development of forkhead-winged helix box transcription factor 3(+) regulatory T cells (Tregs) in thymus. However, the type of APCs that are responsible for selecting Tregs has remained unclear. To...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325783/ https://ncbi.nlm.nih.gov/pubmed/20802149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900665 |
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