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OX40 ligand shuts down IL-10-producing regulatory T cells

IL-10-producing CD4(+) type 1 regulatory T (Tr1) cells play a critical role in the maintenance of peripheral tolerance. Although immunosuppressive drugs, cytokines, costimulatory molecules, and immature dendritic cells are implicated in the induction of Tr1 cells, the signals that negatively regulat...

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Détails bibliographiques
Auteurs principaux: Ito, Tomoki, Wang, Yui-Hsi, Duramad, Omar, Hanabuchi, Shino, Perng, Olivia A., Gilliet, Michel, Qin, F. Xiao-Feng, Liu, Yong-Jun
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559766/
https://ncbi.nlm.nih.gov/pubmed/16924108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603107103
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