Analyzing Th17 cell differentiation dynamics using a novel integrative modeling framework for time-course RNA sequencing data

BACKGROUND: The differentiation of naive CD 4(+) helper T (Th) cells into effector Th17 cells is steered by extracellular cytokines that activate and control the lineage specific transcriptional program. While the inducing cytokine signals and core transcription factors driving the differentiation t...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :BMC Syst Biol
Главные авторы: Intosalmi, Jukka, Ahlfors, Helena, Rautio, Sini, Mannerstöm, Henrik, Chen, Zhi Jane, Lahesmaa, Riitta, Stockinger, Brigitta, Lähdesmäki, Harri
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650136/
https://ncbi.nlm.nih.gov/pubmed/26578352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0223-6
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы