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Analyzing Th17 cell differentiation dynamics using a novel integrative modeling framework for time-course RNA sequencing data
BACKGROUND: The differentiation of naive CD 4(+) helper T (Th) cells into effector Th17 cells is steered by extracellular cytokines that activate and control the lineage specific transcriptional program. While the inducing cytokine signals and core transcription factors driving the differentiation t...
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| Veröffentlicht in: | BMC Syst Biol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4650136/ https://ncbi.nlm.nih.gov/pubmed/26578352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0223-6 |
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