Analyzing Th17 cell differentiation dynamics using a novel integrative modeling framework for time-course RNA sequencing data

BACKGROUND: The differentiation of naive CD 4(+) helper T (Th) cells into effector Th17 cells is steered by extracellular cytokines that activate and control the lineage specific transcriptional program. While the inducing cytokine signals and core transcription factors driving the differentiation t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Syst Biol
Prif Awduron: Intosalmi, Jukka, Ahlfors, Helena, Rautio, Sini, Mannerstöm, Henrik, Chen, Zhi Jane, Lahesmaa, Riitta, Stockinger, Brigitta, Lähdesmäki, Harri
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650136/
https://ncbi.nlm.nih.gov/pubmed/26578352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0223-6
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