Antiviral Phosphorodiamidate Morpholino Oligomers are Protective against Chikungunya Virus Infection on Cell-based and Murine Models

Chikungunya virus (CHIKV) infection in human is associated with debilitating and persistent arthralgia and arthritis. Currently, there is no specific vaccine or effective antiviral available. Anti-CHIKV Phosphorodiamidate Morpholino Oligomer (CPMO) was evaluated for its antiviral efficacy and cytoto...

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Publicat a:Sci Rep
Autors principals: Lam, Shirley, Chen, Huixin, Chen, Caiyun Karen, Min, Nyo, Chu, Justin Jang Hann
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649900/
https://ncbi.nlm.nih.gov/pubmed/26224141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12727
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