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Antisense Phosphorodiamidate Morpholino Oligomers as Novel Antiviral Compounds
Phosphorodiamidate morpholino oligomers (PMO) are short single-stranded DNA analogs that are built upon a backbone of morpholine rings connected by phosphorodiamidate linkages. As uncharged nucleic acid analogs, PMO bind to complementary sequences of target mRNA by Watson–Crick base pairing to block...
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| Publicado no: | Front Microbiol |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5920040/ https://ncbi.nlm.nih.gov/pubmed/29731743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00750 |
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