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Caspase-1 cleavage of transcription factor GATA4 and regulation of cardiac cell fate

Caspase-1 or interleukin-1β (IL-1β) converting enzyme is a pro-inflammatory member of the caspase family. An IL-1β-independent role for caspase-1 in cardiomyocyte cell death and heart failure has emerged but the mechanisms underlying these effects are incompletely understood. Here, we report that tr...

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Publicat a:Cell Death Dis
Autors principals: Aries, A, Whitcomb, J, Shao, W, Komati, H, Saleh, M, Nemer, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649840/
https://ncbi.nlm.nih.gov/pubmed/25501827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.524
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