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Complementation of Yeast Genes with Human Genes as an Experimental Platform for Functional Testing of Human Genetic Variants

While the pace of discovery of human genetic variants in tumors, patients, and diverse populations has rapidly accelerated, deciphering their functional consequence has become rate-limiting. Using cross-species complementation, model organisms like the budding yeast, Saccharomyces cerevisiae, can be...

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Detaylı Bibliyografya
Yayımlandı:Genetics
Asıl Yazarlar: Hamza, Akil, Tammpere, Erik, Kofoed, Megan, Keong, Christelle, Chiang, Jennifer, Giaever, Guri, Nislow, Corey, Hieter, Philip
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Genetics Society of America 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649650/
https://ncbi.nlm.nih.gov/pubmed/26354769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.181099
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