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Cross-Species Complementation of Nonessential Yeast Genes Establishes Platforms for Testing Inhibitors of Human Proteins

Cross-species complementation can be used to generate humanized yeast, which is a valuable resource with which to model and study human biology. Humanized yeast can be used as an in vivo platform to screen for chemical inhibition of human protein drug targets. To this end, we report the systematic c...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Hamza, Akil, Driessen, Maureen R. M., Tammpere, Erik, O’Neil, Nigel J., Hieter, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054014/
https://ncbi.nlm.nih.gov/pubmed/31937519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302971
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