MicroRNAs and Their Targets Are Differentially Regulated in Adult and Neonatal Mouse CD8+ T Cells

Immunological memory, which protects organisms from re-infection, is a hallmark of the mammalian adaptive immune system and the underlying principle of vaccination. In early life, however, mice and other mammals are deficient at generating memory CD8+ T cells, which protect organisms from intracellu...

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Bibliographic Details
Published in:Genetics
Main Authors: Wissink, Erin M., Smith, Norah L., Spektor, Roman, Rudd, Brian D., Grimson, Andrew
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2015
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649632/
https://ncbi.nlm.nih.gov/pubmed/26416483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.179176
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