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miR-150 Regulates Differentiation and Cytolytic Effector Function in CD8+ T cells

MicroRNAs regulate most mammalian genes, and they control numerous aspects of immune system development and function. Their precise roles in the CD8+ T cell response, however, remain unclear. In this report, we show that in the absence of the microRNA miR-150, CD8+ T cells fail to undergo robust exp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Smith, Norah L., Wissink, Erin M., Grimson, Andrew, Rudd, Brian D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637875/
https://ncbi.nlm.nih.gov/pubmed/26549197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16399
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