General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.

Transcription of the human erythropoietin (EPO) gene is activated in Hep3B cells exposed to hypoxia. Hypoxia-inducible factor 1 (HIF-1) is a nuclear factor whose DNA binding activity is induced by hypoxia in Hep3B cells, and HIF-1 binds at a site in the EPO gene enhancer that is required for hypoxic...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Wang, G L, Semenza, G L
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1993
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46495/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8387214/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.9.4304
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