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General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.

Transcription of the human erythropoietin (EPO) gene is activated in Hep3B cells exposed to hypoxia. Hypoxia-inducible factor 1 (HIF-1) is a nuclear factor whose DNA binding activity is induced by hypoxia in Hep3B cells, and HIF-1 binds at a site in the EPO gene enhancer that is required for hypoxic...

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Bibliografski detalji
Glavni autori: Wang, G L, Semenza, G L
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC46495/
https://ncbi.nlm.nih.gov/pubmed/8387214
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