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Parenteral Administration of Capsule Depolymerase EnvD Prevents Lethal Inhalation Anthrax Infection

Left untreated, inhalation anthrax is usually fatal. Vegetative forms of Bacillus anthracis survive in blood and tissues during infection due to elaboration of a protective poly-γ-d-glutamic acid (PDGA) capsule that permits uncontrolled bacterial growth in vivo, eventually leading to overwhelming ba...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Negus, David, Vipond, Julia, Hatch, Graham J., Rayner, Emma L., Taylor, Peter W.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649238/
https://ncbi.nlm.nih.gov/pubmed/26438506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01547-15
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